نتایج جستجو برای: Binding activity

تعداد نتایج: 1458554  

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه رازی - دانشکده علوم 1391

we have two part in this thesis, at first: the interaction of native calf thymus dna (ct-dna) with two anthraquinones including quinizarin (1,4- dihydroxy anthraquinone) and danthron (1,8- dihydroxy anthraquinone) in a mixture of 0.04 m brittone-robinson buffer and 50% of ethanol were studied at physiological ph by uv-vis absorption, florescence, circular dichroism spectroscopic methods, viscos...

Journal: :iranian journal of pharmaceutical research 0
aa moshtaghie a badii m fazilati t hassanzadeh h kharazi

the characteristics of manganese and iron binding to human apotransferrin (apo-tf) have been investigated and compared in this study. both metal ions were taken up by human apo-tf and formed complexes, with the maximum absorbances observed at 410 and 340 nm for manganese-transferrin (mn-tf) and 465 nm for iron-transferrin (fe-tf). addition of manganese (1.5 µg/ml) to the reaction mixture contai...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تبریز - دانشکده علوم طبیعی 1391

in recent years many researchers have been focused on interaction of small molecules with dna. dna is generally the primary intracellular of anticancer drugs, so the interaction between small molecules and dna can cause dna damage in cancer cells, blocking the division of cancer cells and resulting in cell death. the flavonoids are a large group of polyphenolic natural products that are widely ...

Journal: :iranian journal of basic medical sciences 0
jamshid faghri department of bacteriology and virology, faculty of medicine , isfahan university of medical sciences, isfahan, iran delavar shahbazzadeh biotechnology research centre, pasteur institute of iran, tehran, iran kamran pooshang bagheri biotechnology research centre, pasteur institute of iran, tehran, iran sharareh moghim department of bacteriology and virology, faculty of medicine , isfahan university of medical sciences, isfahan, iran hajieh ghasemian safaei department of bacteriology and virology, faculty of medicine , isfahan university of medical sciences, isfahan, iran bahram nasr esfahani department of bacteriology and virology, faculty of medicine , isfahan university of medical sciences, isfahan, iran

objective(s) staphylococcus aureus is a foremost source of numerous nosocomial and community acquired infections. antibiotic therapy for vancomycin resistant s. aureus (vrsa) can not promise the eradication of infections. since adhesion is the major route of infections, adhesin based vaccine could suppress s. aureus infections. fibronectin binding protein a (fnbpa) and clumping factor a (clfa) ...

Bahram Nasr Esfahani Delavar Shahbazzadeh Hajieh Ghasemian Safaei Hamid Mirmohammad Sadeghi Hossein Fazeli, Jamshid Faghri, Kamran Pooshang Bagheri, Rahmatolah Yazdani Sharareh Moghim,

Objective(s) Staphylococcus aureus is a foremost source of numerous nosocomial and community acquired infections. Antibiotic therapy for vancomycin resistant S. aureus (VRSA) can not promise the eradication of infections. Since adhesion is the major route of infections, adhesin based vaccine could suppress S. aureus infections. Fibronectin binding protein A (FnBPA) and clumping factor A (ClfA)...

Journal: Mycologia Iranica 2016

Evidence for the role of chitinases in biocontrol by Trichoderma species has been well documented.Chit42 lacks a chitin–binding domain (ChBD) which is involved in its binding activity to insoluble chitin. The objective of the present study was to enhance antifungal activity of T. harzianum by overexpression of wild type and hybrid forms of Chit42 containing chitin binding domain. To produce chi...

Journal: :iranian journal of biotechnology 2015
thu ngoc le thi huyen do thanh nhan nguyen ngoc tan tran sven olof enfors

background: enterocin-p of enterococcus faecium p13 (entp) is of great interest as a food preservative and medicine due to its non-toxicity and broad antimicrobial spectrum in various ph, as well as its excellent thermal stability. however, recombinant production of entp is still in laboratory because of low productivity and complex purification process. objectives: in this study, we aimed to d...

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد علوم دارویی - دانشکده داروسازی 1393

با توجه به حیاتی بودن نقش آنزیم topo ii در چرخه سلولی، این آنزیم میتواند هدف درمانی مهمی در شیمی درمانی سرطان باشد. فلوروکینولون ها به عنوان مهارکننده های آنزیم توپوایزومراز (ژیراز) باکتری به خوبی شناخته شده اند و اخیرا نیز نشان داده شده است که توان مهار توپوایزومراز ii یوکاریوتیکها را هم دارند. در این راستا در این پایان نامه ترکیبات جدیدی از فلوروکینولونها به منظور مهار آنزیم توپوایزومراز انسا...

Journal: :acta medica iranica 0
ramina mahboobi department of pathobiology, school of public health, tehran university of medical sciences, tehran, iran. davoud afshar department of pathobiology, school of public health, tehran university of medical sciences, tehran, iran. mohammad reza pourmand department of pathobiology, school of public health, tehran university of medical sciences, tehran, iran. rahil mashhadi urology research center, tehran university of medical sciences, tehran, iran.

pneumococcal autolysins are enzymes involved in cell wall turnover and cellular division physiologically. they have been found to be involved in the pneumococcus pathogenesis. the aim of this study was to identify the autolytic activity of spr1754 as a novel protein of streptococcus pneumoniae . moreover, the binding of the recombinant protein to plasma proteins was also determined. the spr1754...

A Badii AA Moshtaghie H Kharazi M Fazilati T Hassanzadeh

The characteristics of manganese and iron binding to human apotransferrin (apo-tf) have been investigated and compared in this study. Both metal ions were taken up by human apo-tf and formed complexes, with the maximum absorbances observed at 410 and 340 nm for manganese-transferrin (Mn-tf) and 465 nm for iron-transferrin (Fe-tf). Addition of manganese (1.5 µg/ml) to the reaction mixture contai...

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